Preclinical studies of immunomicelles incorporating anticancer drugs

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Predictive value of preclinical toxicology studies for platinum anticancer drugs.

Rodent and nonrodent toxicology studies are currently expected to support Phase I trials of antineoplastic drugs in the United States. To determine the predictive value of these studies, we initiated a project to compare preclinical and clinical toxicity data within various drug classes. The first class analyzed was the platinum anticancer drugs. Twelve platinum analogues that had both preclini...

متن کامل

New preclinical strategies for characterization and development of anticancer drugs

Karlsson, H. 2017. New preclinical strategies for characterization and development of anticancer drugs. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1378. 59 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0101-3. Increased understanding of the molecular mechanisms underlying cancer development has shifted drug discovery towards target drive...

متن کامل

Preclinical screening of anticancer drugs using infrared (IR) microspectroscopy.

High-throughput label-free technologies such as IR microscopy can objectively assess the effect of drugs upon cellular systems, offering the potential of a valuable preclinical tool that can aid in the drug development process.

متن کامل

Anticancer potential of curcumin: preclinical and clinical studies.

Curcumin (diferuloylmethane) is a polyphenol derived from the plant Curcuma longa, commonly called turmeric. Extensive research over the last 50 years has indicated this polyphenol can both prevent and treat cancer. The anticancer potential of curcumin stems from its ability to suppress proliferation of a wide variety of tumor cells, down-regulate transcription factors NF-kappa B, AP-1 and Egr-...

متن کامل

Immunomicelles: targeted pharmaceutical carriers for poorly soluble drugs.

To prepare immunomicelles, new targeted carriers for poorly soluble pharmaceuticals, a procedure has been developed to chemically attach mAbs to reactive groups incorporated into the corona of polymeric micelles made of polyethylene glycol-phosphatidylethanolamine conjugates. Micelle-attached antibodies retained their ability to specifically interact with their antigens. Immunomicelles with att...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Drug Delivery System

سال: 2019

ISSN: 0913-5006,1881-2732

DOI: 10.2745/dds.34.29